College football odds Week 1: How to bet Notre Dame-Ohio State


Notre Dame and Ohio State will face off in a college football, Week 1 prime-time matchup between two legendary football programs.

The Buckeyes will play host to the Fighting Irish at Ohio Stadium as the teams begin their quests to make it to the College Football Playoff (CFP) National Championship Game.

Both of these squads finished 2021 with 11-2 records, but which team gets the edge in the Saturday night showdown? 

Here’s everything you need from a betting perspective on the game between Notre Dame and Ohio State from the point spread, moneyline and total over/under (odds via FOX Bet).

No. 5 Notre Dame @ No. 2 Ohio State (7:30 p.m. ET Saturday, ABC)

Point spread: Ohio State -17 (Ohio State favored to win by more than 17 points, otherwise Notre Dame covers)
Moneyline: Ohio State -714 favorite to win (bet $10 to win $11.40 total); Notre Dame +500 underdog to win (bet $10 to win $60 total)
Total scoring over/under: 54.5 points scored by both teams combined

5

Notre Dame Fighting Irish

ND

2

Ohio State Buckeyes

OSU

Being listed as 17-point underdogs like the Irish are against the Buckeyes could easily cause low morale among a coaching staff and throughout a team. But this is not the case for Notre Dame. Instead, it looks like new head coach Marcus Freeman is using that huge number as motivating bulletin board material for his squad.

“I’m gonna write that down,” Freeman, the first-year HC told The Athletic’s Matt Fortuna. “We’ll use that in a team meeting today. It’s good to know.”

Per FOX Sports Research, the Irish went 9-4 against the spread (ATS) last season. And, since 1982, when Notre Dame has been a double-digit underdog, the squad has gone 20-14 ATS. Two good nuggets for gamblers who are mulling over sprinkling a few bucks on the Irish.

On the other side of the ball is home-team Ohio State. 

The No. 2-ranked Buckeyes won their most recent championship in 2014 when they defeated the Oregon Ducks 42-20. Their last appearance in a CFP title game was in 2020, which ended in a 52-24 loss to the Alabama Crimson Tide.

Based on their history of matchups against Notre Dame, the Buckeyes could be entering this contest confidently. Per FOX Sports Research, the Buckeyes are 4-0 ATS and 4-0 straight up (SU) when playing the Irish since 1995.

And backers debating taking the over or the under of 54.5 points might consider these two programs’ 2021 records in that category. Notre Dame’s games hit the over in seven of 13 games, while Ohio State’s hit the over eight times out of 13.

So will Notre Dame have the luck of the Irish on its side Saturday, or will Ohio State buck its way to its first win of the season? Head over to FOX Bet to get in on the action now!

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